BDBM50501292 CHEMBL3342978
SMILES Fc1ccc(Oc2cc(F)cn3cc(cc23)C#N)c(OCCn2ccc(=O)[nH]c2=O)c1
InChI Key InChIKey=ZZRRYEXYIVBDNM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50501292
Affinity DataEC50: 250nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT2 cells assessed as protection against viral infection by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase p66/p51 expressed in Escherichia coli BL21 (DE3) pLysS cells preincubated followed by primer/tem...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase p66/p51 Y181C mutant expressed in Escherichia coli BL21 (DE3) pLysS cells preincubated followed ...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant infected in human MT2 cells assessed as protection against viral infection by MTT ...More data for this Ligand-Target Pair