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Found 4 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50501292'
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50501292(CHEMBL3342978)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase p66/p51 expressed in Escherichia coli BL21 (DE3) pLysS cells preincubated followed by primer/tem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50501292(CHEMBL3342978)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase p66/p51 Y181C mutant expressed in Escherichia coli BL21 (DE3) pLysS cells preincubated followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50501292(CHEMBL3342978)
Affinity DataEC50:  250nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT2 cells assessed as protection against viral infection by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50501292(CHEMBL3342978)
Affinity DataEC50:  10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant infected in human MT2 cells assessed as protection against viral infection by MTT ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed