BDBM50502388 CHEMBL4525318::US11084784, Example 1
SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)C(OC)(C(F)(F)F)C(F)(F)F)cc1
InChI Key InChIKey=XCYAYGZSVGESNE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50502388
Affinity DataIC50: 32nMAssay Description:Inverse agonist activity at human biotinylated HN-Avi-MBPS-TCS-RORC2 (258 to 518 residues) assessed as recruitment of SRC-1-derived coactivator measu...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:CHO-K1 cells stably transfected with RORĪ³t are maintained in MEM-EBS with 5% FBS, 1% penicillin streptomycin solution and 1 mg/mL G418. The cells ar...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inverse agonist activity at RORC2 in human Th17 cells assessed as inhibition of IL-17A secretion incubated for 4 days by HTRF assayMore data for this Ligand-Target Pair