BDBM50511342 CHEMBL4538474
SMILES OP(O)(=O)Oc1cc(OP(O)(O)=O)c(OP(O)(O)=O)cc1OP(O)(O)=O
InChI Key InChIKey=OFSQKFMVBPORNX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50511342
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
School Of Biological Sciences, Uea
Curated by ChEMBL
School Of Biological Sciences, Uea
Curated by ChEMBL
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of His-tagged SHIP2 (unknown origin) incubated for 5 mins using Ins(1,3,4,5)P4 as substrate by malachite green reagent based phosphate ass...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
School Of Biological Sciences, Uea
Curated by ChEMBL
School Of Biological Sciences, Uea
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Mus musculus)
University Of East Anglia
Curated by ChEMBL
University Of East Anglia
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of SHIP2 in serum-starved mouse Mm1 cells assessed as reduction in Akt phosphorylation incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
School Of Biological Sciences, Uea
Curated by ChEMBL
School Of Biological Sciences, Uea
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
School Of Biological Sciences, Uea
Curated by ChEMBL
School Of Biological Sciences, Uea
Curated by ChEMBL
Affinity DataIC50: 6.93E+4nMAssay Description:Displacement of Ins(1,3,4,5)P4 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetType II inositol 1,4,5-trisphosphate 5-phosphatase(Homo sapiens)
School Of Biological Sciences, Uea
Curated by ChEMBL
School Of Biological Sciences, Uea
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged INPP5B (259 to 563 residues) expressed in Escherichia coli BL21 (DE3) incubated for 5 mins usin...More data for this Ligand-Target Pair