BDBM50513204 CHEMBL4537250

SMILES CC(C)(C)C[C@H]1NC([C@H](c2cccc(Cl)c2F)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@H]1C[C@@](C)(O)C1

InChI Key InChIKey=MZBOZBMARIQZGX-OZSDUJMASA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513204   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513204(CHEMBL4537250)
Affinity DataKi:  0.440nMAssay Description:Inhibition of wild type p53 protein binding to MDM2 in human HCT116 cells by immunoblot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513204(CHEMBL4537250)
Affinity DataKi:  0.440nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed