BDBM50525201 CHEMBL4463124
SMILES CNC[C@@H](O)CN1CCc2c(C1)cccc2OCc1ccc(cc1)-c1nccs1
InChI Key InChIKey=YOIPDYXMOWADRA-HXUWFJFHSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50525201
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of PRMT4 (unknown origin) using histone H3 (21 to 44 residues) as substrate measured after 60 mins in presence of SAM by AlphaLisa assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant full-length human PRMT7 expressed in Sf9 insect cells using Ac-KKDGKKRKRSRKESYK-biotin as substrate measured after 30 mins ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of PRMT1 (unknown origin) preincubated for 15 mins followed by substrate addition and measured after 60 mins by AlphaLisa assayMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 369nMAssay Description:Inhibition of PRMT4 in human MOLM13 cells assessed as reduction in BAF155 dimethylation measured after 96 hrs by Western blotting analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of PRMT6 (unknown origin) preincubated for 15 mins followed by substrate addition and measured after 60 mins by AlphaLisa assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PRMT3 (unknown origin) preincubated for 15 mins followed by substrate addition and measured after 60 mins by AlphaLisa assayMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 545nMAssay Description:Inhibition of PRMT4 in human MOLM13 cells assessed as reduction in PABP1 dimethylation measured after 96 hrs by Western blotting analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) preincubated for 15 mins followed by substrate addition and measured after 60 mins by AlphaLisa assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of PRMT8 (unknown origin) preincubated for 15 mins followed by substrate addition and measured after 60 mins by AlphaLisa assayMore data for this Ligand-Target Pair