Found 3 Enz. Inhib. hit(s) with Target = 'Histone-arginine methyltransferase CARM1' and Ligand = 'BDBM50525201' TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of PRMT4 (unknown origin) using histone H3 (21 to 44 residues) as substrate measured after 60 mins in presence of SAM by AlphaLisa assayMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 369nMAssay Description:Inhibition of PRMT4 in human MOLM13 cells assessed as reduction in BAF155 dimethylation measured after 96 hrs by Western blotting analysisMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 545nMAssay Description:Inhibition of PRMT4 in human MOLM13 cells assessed as reduction in PABP1 dimethylation measured after 96 hrs by Western blotting analysisMore data for this Ligand-Target Pair
