BDBM50527135 CHEMBL4452072
SMILES CN(Cc1ccccc1)c1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O
InChI Key InChIKey=NRCRRUYZIFHEBT-SCFUHWHPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50527135
Affinity DataKi: 0.318nMAssay Description:Inhibition of human CD73More data for this Ligand-Target Pair
Affinity DataKi: 0.381nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 0.746nMAssay Description:Inhibition of recombinant rat CD73 expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.746nMAssay Description:Inhibition of rat CD73More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human C-terminal His6-tagged CD73 expressed in CHO cells preincubated for 15 mins followed by AMP addition and measured after 10 mins b...More data for this Ligand-Target Pair