BDBM50529639 CHEMBL4454809

SMILES COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)[C@H]2CC[C@H](O)CC2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=DMAYUUDCUFRNPK-JTRPPKJJSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50529639   

TargetProteasome subunit beta type-1(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of 20S proteosome beta 1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  262nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  782nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of LMP2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  23nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  782nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  507nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  23nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of MECL1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of 20S proteosome beta 2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  262nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of MECL1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of LMP2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of 20S proteosome beta 1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of 20S proteosome beta 2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529639(CHEMBL4454809)
Affinity DataIC50:  507nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed