BDBM50536429 CHEMBL4581491
SMILES COC1CCC(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)CC1
InChI Key InChIKey=DCZBCXUZOSJEJQ-FQLCGHSNSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50536429
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based compet...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 891nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based competitive a...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based compet...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based competitive a...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair