BDBM50540080 CHEMBL4648857
SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12
InChI Key InChIKey=RUBYHLPRZRMTJO-FLVSMNSFSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50540080
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of CDK13 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant full length human CDK7/C-terminal His-tagged Cyclin H/N-terminal GST-tagged MAT1 expressed in baculovirus in Sf21 insect ce...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant CDK13 (unknown origin) by radiometric kinase assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant CDK12 (unknown origin) expressed in baculovirus infected insect cells using Pol II CTD peptide as substrate in presence of ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant CDK13 (unknown origin) expressed in baculovirus infected insect cells using Pol II CTD peptide as substrate in presence of ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant CDK12/Cyclin K (unknown origin) expresssed in baculovirus infected insect cells using peptide substrate incubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant CDK13/Cyclin K (unknown origin) expresssed in baculovirus infected insect cells using peptide substrate incubated for 30 mi...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant CDK12 (unknown origin) by radiometric kinase assayMore data for this Ligand-Target Pair