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Found 4 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 12' and Ligand = 'BDBM50540080'
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540080(CHEMBL4648857)
Affinity DataIC50:  158nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540080(CHEMBL4648857)
Affinity DataIC50:  158nMAssay Description:Inhibition of recombinant CDK12/Cyclin K (unknown origin) expresssed in baculovirus infected insect cells using peptide substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540080(CHEMBL4648857)
Affinity DataIC50:  158nMAssay Description:Inhibition of recombinant CDK12 (unknown origin) expressed in baculovirus infected insect cells using Pol II CTD peptide as substrate in presence of ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540080(CHEMBL4648857)
Affinity DataIC50:  158nMAssay Description:Inhibition of recombinant CDK12 (unknown origin) by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed