BDBM50548267 CHEMBL4761159

SMILES COc1cccc2C(=O)C3=C([C@H](C)O[C@@H](CC(O)=O)C3)C(=O)c12

InChI Key InChIKey=ROSHODBELPZZPV-DTWKUNHWSA-N

Data  1 KI  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50548267   

TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataKi:  4.90E+3nMAssay Description:Competitive inhibition of human CSE using varying levels of L-Cys as substrate and fixed PLP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by LC/MS/MS-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to human CSE by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50:  6.20E+3nMAssay Description:Non-covalent reversible inhibition of human CSEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed