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Found 6 Enz. Inhib. hit(s) with Target = 'Cystathionine gamma-lyase' and Ligand = 'BDBM50548267'
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataKi:  4.90E+3nMAssay Description:Competitive inhibition of human CSE using varying levels of L-Cys as substrate and fixed PLP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50:  6.20E+3nMAssay Description:Non-covalent reversible inhibition of human CSEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by LC/MS/MS-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to human CSE by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed