BDBM50550642 CHEMBL4787081
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)NCC(C)(C)C)NS(=O)(=O)c1ccc(C)cc1)B(O)O
InChI Key InChIKey=DPFMPSWJJIWBOL-GSDHBNRESA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50550642
TargetProteasome subunit beta type-1(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of human 20S constitutive proteasome beta 2 subunit trypsin-like activity using fluorogenic peptide Ac-WLR-AMC as substrate in presence of...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human 20S immunoproteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence of PA2...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-10(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human 20S immunoproteasome beta 2 subunit trypsin-like activity using fluorogenic peptide Ac-WLR-AMC as substrate in presence of PA28al...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presen...More data for this Ligand-Target Pair