BDBM50554259 CHEMBL4788026

SMILES O=c1n(Cc2ccccc2)cnc2cc(ccc12)-c1cn[nH]c1

InChI Key InChIKey=GAVLIPSZXZKQHK-UHFFFAOYSA-N

Data  1 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554259   

TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554259(CHEMBL4788026)
Affinity DataKd:  3.33E+3nMAssay Description:Binding affinity to full length human GRK2 by Thermofluor thermal shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554259(CHEMBL4788026)
Affinity DataKd: >8.33E+4nMAssay Description:Binding affinity to GRK5 (unknown origin) by Thermofluor thermal shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRhodopsin kinase GRK1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554259(CHEMBL4788026)
Affinity DataKd:  4.76E+4nMAssay Description:Binding affinity to GRK1 (unknown origin) by Thermofluor thermal shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554259(CHEMBL4788026)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB