BDBM50563665 CHEMBL4785754

SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](OC(=O)[C@H](CCSC)NC(=O)OC(C)(C)C)C(C)(C)[C@]3([H])CC[C@@]21C)[C@]1(C)CC[C@@H](O1)C(C)(C)O

InChI Key InChIKey=JXWWZNPMQPMYET-GHVJQWSNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50563665   

TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Universities Of Shandong

Curated by ChEMBL
LigandPNGBDBM50563665(CHEMBL4785754)
Affinity DataIC50: >5.00E+3nMAssay Description:Reversal of MRP2-mediated multidrug resistance in human KBV cells assessed as cisplatin IC50 at 5 uM after 72 hrs in presence of cisplatin by MTT ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universities Of Shandong

Curated by ChEMBL
LigandPNGBDBM50563665(CHEMBL4785754)
Affinity DataIC50:  748nMAssay Description:Reversal of BCRP-mediated multidrug resistance in human KBV cells assessed as mitoxantrone IC50 at 10 uM after 72 hrs in presence of mitoxantrone by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universities Of Shandong

Curated by ChEMBL
LigandPNGBDBM50563665(CHEMBL4785754)
Affinity DataIC50:  843nMAssay Description:Reversal of BCRP-mediated multidrug resistance in human KBV cells assessed as mitoxantrone IC50 at 5 uM after 72 hrs in presence of mitoxantrone by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Universities Of Shandong

Curated by ChEMBL
LigandPNGBDBM50563665(CHEMBL4785754)
Affinity DataIC50: >5.00E+3nMAssay Description:Reversal of MRP2-mediated multidrug resistance in human KBV cells assessed as cisplatin IC50 at 10 uM after 72 hrs in presence of cisplatin by MTT as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed