BDBM50573844 CHEMBL4873042

SMILES CN(C)CCCn1ccc2cc(ccc12)-c1nc(nc2[nH]ccc12)S(C)(=O)=O

InChI Key InChIKey=PNAZPTARVAORJD-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50573844   

TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Fujian Medical University

Curated by ChEMBL
LigandPNGBDBM50573844(CHEMBL4873042)
Affinity DataIC50:  27nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Fujian Medical University

Curated by ChEMBL
LigandPNGBDBM50573844(CHEMBL4873042)
Affinity DataEC50:  120nMAssay Description:Displacement of Halo-tagged histone H4 from NanoLuc-tagged BPTF (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Fujian Medical University

Curated by ChEMBL
LigandPNGBDBM50573844(CHEMBL4873042)
Affinity DataKd:  2.07E+4nMAssay Description:Binding affinity to N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by SPR assayMore data for this Ligand-Target Pair