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Found 3 Enz. Inhib. hit(s) with Target = 'Nucleosome-remodeling factor subunit BPTF' and Ligand = 'BDBM50573844'
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Fujian Medical University

Curated by ChEMBL
LigandPNGBDBM50573844(CHEMBL4873042)
Affinity DataIC50:  27nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Fujian Medical University

Curated by ChEMBL
LigandPNGBDBM50573844(CHEMBL4873042)
Affinity DataEC50:  120nMAssay Description:Displacement of Halo-tagged histone H4 from NanoLuc-tagged BPTF (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Fujian Medical University

Curated by ChEMBL
LigandPNGBDBM50573844(CHEMBL4873042)
Affinity DataKd:  2.07E+4nMAssay Description:Binding affinity to N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by SPR assayMore data for this Ligand-Target Pair