BDBM50583624 CHEMBL5075135
SMILES ONC(=O)c1ccc(CN(Cc2cccnc2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1
InChI Key InChIKey=HBOMISXRZUHCSH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50583624
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human HDAC6 by jump dilution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC6 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.65E+3nMAssay Description:Inhibition of full length human HDAC5 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human HDAC6 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length human HDAC4 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.29E+3nMAssay Description:Inhibition of full length human HDAC7 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of full length human HDAC2 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 921nMAssay Description:Inhibition of full length human HDAC1 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 373nMAssay Description:Inhibition of full length human HDAC3 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of full length human HDAC9 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 572nMAssay Description:Inhibition of full length human HDAC10 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human HDAC6 using FAM-labeled acetylated peptide as substrate without preincubation by mass spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human HDAC6 preincubated for 3 hrs by mass spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of full length human HDAC8 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length human HDAC11 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair