BDBM525055 US11168102, Example 8-4.
SMILES C[C@@H](Nc1ncnc2n(C)c(=O)c(cc12)C1CCN(CCF)CC1)c1cccc(C(F)F)c1F
InChI Key InChIKey=OWSYEZSQVSCOFJ-CQSZACIVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 525055
Affinity DataIC50: 7.66nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
Affinity DataKd: 29.4nMAssay Description:The purpose of this assay was to characterize the inhibitory activity of compounds on SOS1 nucleotide exchange of KRAS. Data was reported as IC50 val...More data for this Ligand-Target Pair