Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Son of sevenless homolog 1 [564-1049]' and Ligand = 'BDBM525055'
TargetSon of sevenless homolog 1 [564-1049]()
Revolution Medicines

US Patent
LigandPNGBDBM525055(US11168102, Example 8-4.)
Affinity DataIC50:  7.66nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1 [564-1049]()
Revolution Medicines

US Patent
LigandPNGBDBM525055(US11168102, Example 8-4.)
Affinity DataKd:  29.4nMAssay Description:The purpose of this assay was to characterize the inhibitory activity of compounds on SOS1 nucleotide exchange of KRAS. Data was reported as IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent