BDBM545132 US11286268, Compound 618

SMILES CN(Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F)C(C)(C)C

InChI Key InChIKey=WRSTZBIWTPVKRP-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 545132   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
eFFECTOR Therapeutics, Inc.

US Patent
LigandPNGBDBM545132(US11286268, Compound 618)
Show SMILES CN(Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F)C(C)(C)C
Show InChI InChI=1S/C34H32ClF2N5O5S/c1-17-11-22(30-28(39-17)24(16-48-30)32(44)45)21-13-20(35)7-8-26(21)46-10-9-42-18(2)40-25-12-19(15-41(6)34(3,4)5)29(47-33(36)37)23(14-38)27(25)31(42)43/h7-8,11-13,16,33H,9-10,15H2,1-6H3,(H,44,45)
Affinity DataIC50: 2.98nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid