BDBM577174 8-Acetyl-10-(4-chlorophenyl)-7,8-dihydropyrido[2',3':4,5]pyrrolo[1,2-a]pyrazin-9(6H)-one::US11472805, Example 78

SMILES CC(=O)N1CCn2c(c(-c3ccc(Cl)cc3)c3ncccc23)C1=O

InChI Key InChIKey=ZWUUJARXAHEDDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 577174   

LigandPNGBDBM577174(8-Acetyl-10-(4-chlorophenyl)-7,8-dihydropyrido[2',...)
Affinity DataIC50:  30.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM577174(8-Acetyl-10-(4-chlorophenyl)-7,8-dihydropyrido[2',...)
Affinity DataIC50:  59.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent