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Found 97 Enz. Inhib. hit(s) with Target = 'Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) [50-672]'
LigandPNGBDBM577126(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  9.07nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577123(10-(4-Chloro-5-fluoro-2-methylphenyl)-8-cyclopropy...)
Affinity DataIC50:  12.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577135(8-Cyclopropyl-10-(3,4,5-trifluorophenyl)-7,8-dihyd...)
Affinity DataIC50:  17.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577143(10-(3-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...)
Affinity DataIC50:  19.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577172(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-3,4,7,8...)
Affinity DataIC50:  21.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577128(2-Chloro-5-(8-cyclopropyl-9-oxo-6,7,8,9-tetrahydro...)
Affinity DataIC50:  23.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577130(10-(3-Chloro-4-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  28.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577094((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...)
Affinity DataIC50:  28.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577182(10-Cyclopentyl-8-cyclopropyl-7,8-dihydropyrido[2',...)
Affinity DataIC50:  29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577174(8-Acetyl-10-(4-chlorophenyl)-7,8-dihydropyrido[2',...)
Affinity DataIC50:  30.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577079(4-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2&...)
Affinity DataIC50:  36.3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM577152(10-(4-Chlorophenyl)-8-(5-methyl-1,2-oxazol-3-yl)-7...)
Affinity DataIC50:  38.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577176(10-(4-Chlorophenyl)-N-ethyl-9-oxo-6,7-dihydropyrid...)
Affinity DataIC50:  42.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577101(4-(8-Cyclopropyl-9-oxo-3,4,6,7,8,9-hexahydro-2H-py...)
Affinity DataIC50:  45.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577173(10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...)
Affinity DataIC50:  56.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577077(10-(4-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...)
Affinity DataIC50:  75.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577102(10-(4-Chlorophenyl)-8-propyl-7,8-dihydropyrido[2',...)
Affinity DataIC50:  81nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577122(4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...)
Affinity DataIC50:  85.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577125(10-(4-Chlorophenyl)-8-ethyl-7,8-dihydropyrido[2',3...)
Affinity DataIC50:  87.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577091(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  88.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577168(4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...)
Affinity DataIC50:  90.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577131(8-Cyclopropyl-10-(4-fluoro-3-methylphenyl)-7,8-dih...)
Affinity DataIC50:  98.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577166(4-(8-Cyclopropyl-9-oxo-8,9-dihydropyrido[2',3':4,5...)
Affinity DataIC50:  108nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577175(10-(4-Chlorophenyl)-8-(methylsulfonyl)-7,8-dihydro...)
Affinity DataIC50:  120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577115(8-Cyclopropyl-10-(3,5-difluoro-4-methoxyphenyl)-7,...)
Affinity DataIC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577136(8-Cyclopropyl-10-(3-fluorophenyl)-7,8-dihydropyrid...)
Affinity DataIC50:  130nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577192(10-(4-Chlorophenyl)-8-(6-methoxyhexyl)-7,8-dihydro...)
Affinity DataIC50:  137nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577120(5-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2'...)
Affinity DataIC50:  138nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577129(8-Cyclopropyl-10-(2,3-dihydro-1-benzofuran-5-yl)-7...)
Affinity DataIC50:  141nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577142(10-(4-Chloro-2-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  142nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577078((6aR)-12-(4-Chlorophenyl)-6a, 7,8,9-tetrahydro-6H,...)
Affinity DataIC50:  150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577090(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  159nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577096(8-Cyclopropyl-10-(4-methylphenyl)pyrido[2′,3...)
Affinity DataIC50:  182nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577141(8-Cyclopropyl-10-(2,5-difluorophenyl)-7,8-dihydrop...)
Affinity DataIC50:  203nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577139(8-Cyclopropyl-10-(4-methoxyphenyl)-7,8-dihydropyri...)
Affinity DataIC50:  212nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577151(10-(4-Chloro-2-methylphenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  253nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577140(8-Cyclopropyl-10-(3-fluoro-4-methoxyphenyl)-7,8-di...)
Affinity DataIC50:  281nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577171(10-(4-Chlorophenyl)-8-cyclopropyl-3,4,7,8-tetrahyd...)
Affinity DataIC50:  286nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577154(8-Cyclopropyl-10-(3,5-difluoro-4-methoxyphenyl)-7,...)
Affinity DataIC50:  290nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577114(8-Cyclopropyl-10-(4-fluorophenyl)-7,8-dihydropyrid...)
Affinity DataIC50:  321nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577103(10-(4-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrro...)
Affinity DataIC50:  345nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577145(4-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2'...)
Affinity DataIC50:  356nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577144(8-Cyclopropyl-10-(4-fluoro-2-methylphenyl)-7,8-dih...)
Affinity DataIC50:  395nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577155(3-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2'...)
Affinity DataIC50:  397nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577148(8-Cyclopropyl-10-(6-methoxypyridin-3-yl)-7,8-dihyd...)
Affinity DataIC50:  426nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577121(9-(4-Chlorophenyl)-7-cyclopropyl-6,7-dihydro[1,3]t...)
Affinity DataIC50:  434nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577100(10-(4-Chloro-2-fluoro-5-methoxyphenyl)-8-cycloprop...)
Affinity DataIC50:  442nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577160(8-Cyclopropyl-10-(furo[3,2-b]pyridin-6-yl)-7,8-dih...)
Affinity DataIC50:  458nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577162(8-Cyclopropyl-10-(2,4-dimethyl-phenyl)pyrido[2',3'...)
Affinity DataIC50:  460nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577107(8-Cyclopropyl-10-(4-methylphenyl)-7,8-dihydropyrid...)
Affinity DataIC50:  465nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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