BDBM605358 US11667652, Example 152
SMILES COc1nn(C)cc1C(=O)N[S@@]1(=O)=NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@H]4[C@H]4O[C@H](CCN(C)C)C[C@@H]4CC[C@H](C)C1)c3c2
InChI Key InChIKey=FBNCBWZEIATGTK-CRUCFZDTSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 605358
TargetBcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair