BDBM60991 BDBM50425048::US9402842, 14

SMILES Cn1c2-c3ccccc3C(=O)c2c2ccc(NC(=O)C(O)=O)cc2c1=O

InChI Key InChIKey=SGJPENVWCVSRKV-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60991   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM60991(BDBM50425048 | US9402842, 14)
Affinity DataIC50:  6.10E+4nMpH: 7.5 T: 2°CAssay Description:A 5′-[32P]-labeled single-stranded DNA oligonucleotide containing a 3′-phosphotyrosine (N14Y) was generated as described by Dexheimer et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM60991(BDBM50425048 | US9402842, 14)
Affinity DataKd:  3.10E+4nMAssay Description:Binding affinity to recombinant Tdp1 (unknown origin) using 3'-phosphate(GATCTAAAAGACTT) as substrate by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM60991(BDBM50425048 | US9402842, 14)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed