BDBM628473 US20230339856, Compound (IIc)

SMILES c1ccc(cc1)CC[C@]2([C@H]([C@@H]([C@H](CN2)O)O)O)CO

InChI Key InChIKey=UJNGRUVYUAYPHC-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 628473   

TargetLysosomal alpha-glucosidase(Human)
UniversitÉ

US Patent
LigandChemical structure of BindingDB Monomer ID 628473BDBM628473(US20230339856, Compound (IIc))
Affinity DataIC50: 220nMAssay Description:The rhGAA enzyme sold under the name Myozyme used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetLysosomal alpha-glucosidase(Human)
UniversitÉ

US Patent
LigandChemical structure of BindingDB Monomer ID 628473BDBM628473(US20230339856, Compound (IIc))
Affinity DataKi:  7.60E+3nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetLysosomal alpha-glucosidase(Human)
UniversitÉ

US Patent
LigandChemical structure of BindingDB Monomer ID 628473BDBM628473(US20230339856, Compound (IIc))
Affinity DataIC50: 3.72E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)