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Found 3 Enz. Inhib. hit(s) with Target = 'Lysosomal alpha-glucosidase' and Ligand = 'BDBM628473'
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628473(US20230339856, Compound (IIc))
Affinity DataKi:  7.60E+3nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628473(US20230339856, Compound (IIc))
Affinity DataIC50:  220nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628473(US20230339856, Compound (IIc))
Affinity DataIC50:  3.72E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent