BDBM65515 76343-93-6::LAT-A::LatA::Latrunculin A

SMILES C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]2CSC(=O)N2)OC(=O)\C=C(C)/CC\C=C\C=C/1

InChI Key InChIKey=DDVBPZROPPMBLW-IZGXTMSKSA-N

Data  5 IC50

PDB links: 18 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 65515   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Louisana

Curated by ChEMBL
LigandPNGBDBM65515(76343-93-6 | LAT-A | LatA | Latrunculin A)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells by cell based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Louisana

Curated by ChEMBL
LigandPNGBDBM65515(76343-93-6 | LAT-A | LatA | Latrunculin A)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells by cell based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed