BDBM82151 7-substituted pyrazoloquinolone, 10

SMILES OC(=O)c1cc2nc3ccc(Br)cc3c(=O)n2[nH]1

InChI Key InChIKey=ONEJWZAOWJIWSA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82151   

TargetPhosphopantetheine adenylyltransferase(Escherichia coli)
Pfizer

LigandPNGBDBM82151(7-substituted pyrazoloquinolone, 10)
Affinity DataIC50:  6.20E+3nMAssay Description:PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphopantetheine adenylyltransferase(Escherichia coli)
Pfizer

LigandPNGBDBM82151(7-substituted pyrazoloquinolone, 10)
Affinity DataIC50:  2.20E+4nMAssay Description:The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphopantetheine adenylyltransferase(Enterococcus faecalis (Streptococcus faecalis))
Pfizer

LigandPNGBDBM82151(7-substituted pyrazoloquinolone, 10)
Affinity DataIC50:  2.09E+5nMAssay Description:PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed