BDBM82411 CAS_75921-69-6::NDP-MSH
SMILES CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
InChI Key InChIKey=UAHFGYDRQSXQEB-LEBBXHLNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 82411
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Uppsala
Curated by PDSP Ki Database
Uppsala
Curated by PDSP Ki Database
Affinity DataEC50: 0.5nMAssay Description:Agonist potency for human Melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist potency towards human Melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0170nMAssay Description:Evaluated for agonist activity at cloned mammalian Melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.132nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Uppsala
Curated by PDSP Ki Database
Uppsala
Curated by PDSP Ki Database
Affinity DataEC50: 0.0230nMAssay Description:Evaluated for agonist activity at cloned mammalian human MSH1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.720nMAssay Description:Effective concentration for intracellular cAMP accumulation in L-cells expressing Melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.510nMAssay Description:Binding affinity towards human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
Affinity DataEC50: 0.580nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 5 receptorMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Uppsala
Curated by PDSP Ki Database
Uppsala
Curated by PDSP Ki Database
Affinity DataEC50: 0.190nMAssay Description:Effective concentration for intracellular cAMP accumulation in L-cells expressing Melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Uppsala
Curated by PDSP Ki Database
Uppsala
Curated by PDSP Ki Database
Affinity DataEC50: 0.190nMAssay Description:effective concentration of peptide at 50% maximal cAMP accumulation on Melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.580nMAssay Description:effective concentration of peptide at 50% maximal cAMP accumulation on Melanocortin 5 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:effective concentration of peptide at 50% maximal cAMP accumulation on Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.720nMAssay Description:effective concentration of peptide at 50% maximal cAMP accumulation on Melanocortin 4 receptorMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Uppsala
Curated by PDSP Ki Database
Uppsala
Curated by PDSP Ki Database
Affinity DataEC50: 0.00500nMAssay Description:Decrease in frog skin reflectivity (melanotropic activity).More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Uppsala
Curated by PDSP Ki Database
Uppsala
Curated by PDSP Ki Database
Affinity DataEC50: 0.0700nMAssay Description:Binding affinity towards human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 0.360nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity on mouse melanocortin 4 receptor (mMC4R) stably expressed in HEL cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity on mouse melanocortin 1 receptor (mMC1R) stably expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 75nMAssay Description:Compound was evaluated for its agonist activity on mouse melanocortin receptor 3 (mMC3R) stably expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Agonist activity on mouse melanocortin 5 receptor (mMC5R) stably expressed in HEL cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Uppsala
Curated by PDSP Ki Database
Uppsala
Curated by PDSP Ki Database
Affinity DataEC50: 0.5nMAssay Description:Agonist activity against human melanocortin receptor hMC1RMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity against human melanocortin receptor hMC4RMore data for this Ligand-Target Pair