BDBM85245 CAS_36322-90-4::NSC_4856::Piroxicam

SMILES CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O

InChI Key InChIKey=QYSPLQLAKJAUJT-UHFFFAOYSA-N

Data  12 KI  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 85245   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataIC50:  2.55E+5nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataIC50:  2.54E+5nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank