BDBM85245 CAS_36322-90-4::NSC_4856::Piroxicam

SMILES CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O

InChI Key InChIKey=QYSPLQLAKJAUJT-UHFFFAOYSA-N

Data  12 KI  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 85245   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  170nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  760nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  2.11E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  2.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  2.68E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  4.88E+3nMAssay Description:TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  7.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  9.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  1.98E+4nMAssay Description:TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 22 member 6(Rattus norvegicus)
Kyorin University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  5.20E+4nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSolute carrier family 22 member 11(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  1.08E+5nMAssay Description:TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT4-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataKi:  1.20E+6nMAssay Description:TP_TRANSPORTER: inhibition of MTX uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank