BDBM86053 B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374

SMILES Nc1nc2CCN(CC=C)CCc2s1

InChI Key InChIKey=DHSSDEDRBUKTQY-UHFFFAOYSA-N

Data  29 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 86053   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  5.80nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataIC50: 25nMAssay Description:Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  37.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  42.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  62.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  67.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  81.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  152nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  162nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  331nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  398nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  513nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  617nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  955nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  977nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  1.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  1.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  2.70E+3nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  3.47E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi:  3.89E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 86053BDBM86053(B-HT 920 | cid_5374 | CAS_101626-70-4 | NSC_104870...)
Affinity DataIC50: 5.00E+5nMAssay Description:Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]-prazosin binding (0.2 nM) to rat isolated brain memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed