BDBM8744 1-[(4-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-imidazole::Disubstituted imidazole 23
SMILES Cc1ccc(Cn2cnc(c2)-c2ccsc2)cc1
InChI Key InChIKey=DHBTWCAOUVLMCW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 8744
Affinity DataIC50: 250nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of Escherichia coli FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of Staphylococcus aureus FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.44E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair