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Found 2 Enz. Inhib. hit(s) with Target = 'Enoyl-[acyl-carrier-protein] reductase [NADH] FabI' and Ligand = 'BDBM8744'
LigandPNGBDBM8744(1-[(4-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)
Affinity DataIC50:  3.92E+3nMAssay Description:Inhibition of Escherichia coli FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM8744(1-[(4-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)
Affinity DataIC50:  6.44E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed