BDBM89034 (1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-diphenyl-sulfanylidenephosphorane;methyl sulfate::(1,2-dimethylimidazo[1,2-a]pyridin-4-ium-3-yl)-diphenyl-sulfanylidene--phosphane;methyl sulfate::(1,2-dimethylimidazo[1,2-a]pyridin-4-ium-3-yl)-diphenyl-thioxo-phosphorane;methyl sulfate::CHEMBL1598051::MLS002703110::SMR001566915::cid_56643192

SMILES Cc1c([n+]2ccccc2n1C)P(=S)(c1ccccc1)c1ccccc1

InChI Key InChIKey=DHDHZKHTNUDMEA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 89034   

TargetProthrombin(Bos taurus (Bovine))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  6.28E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  5.42E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  84nMAssay Description:Displacement of [125I]Tyr10-NPS from neuropeptide S receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed