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Found 6 Enz. Inhib. hit(s) with Target = 'Neuropeptide S receptor' and Ligand = 'BDBM89034'
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  84nMAssay Description:Displacement of [125I]Tyr10-NPS from neuropeptide S receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed