BDBM8958 10-(2-diethylaminopropyl)phenothiazine::CHEMBL1200970::CHEMBL1206::Ethopropazine::diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine

SMILES CCN(CC)C(C)CN1c2ccccc2Sc2ccccc12

InChI Key InChIKey=CDOZDBSBBXSXLB-UHFFFAOYSA-N

Data  11 KI  16 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 8958   

TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataIC50:  2.60E+5nMAssay Description:Inhibition of human plasma AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universit£

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataIC50:  720nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed