BDBM9427 CHEMBL1083790::Heterodimeric Tacrine-Based Inhibitor 5h::N-(9-aminononyl)-1,2,3,4-tetrahydroacridin-9-amine dihydrochloride::N-9-(1,2,3,4-Tetrahydroacridinyl)-1,9-diamino-nonane Bis-hydrochloride
SMILES NCCCCCCCCCNc1c2CCCCc2nc2ccccc12
InChI Key InChIKey=BMSMAYYXXZZRQN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 9427
Affinity DataIC50: 131nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology
Hong Kong University of Science and Technology
Affinity DataIC50: 687nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair