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Found 3 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM9427'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM9427(CHEMBL1083790 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  16nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9427(CHEMBL1083790 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  131nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9427(CHEMBL1083790 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  131nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed