Compile Data Set for Download or QSAR
Report error Found 178 Enz. Inhib. hit(s) with Target = 'Heat shock 70 kDa protein 1A'
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32381(adenosine-derived inhibitor (Grp78), 14 | adenosin...)
Affinity DataKd:  50nMpH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32381(adenosine-derived inhibitor (Grp78), 14 | adenosin...)
Affinity DataKd:  50nMpH: 7.4 T: 2°CAssay Description:All experiments were performed on a Biacore T100 at 25 deg C with a flow rate of 30 uL per minute. Double His-tagged HSP70 was immobilised on the sur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32382(adenosine-derived inhibitor, 16)
Affinity DataKd:  60nMpH: 7.4 T: 2°CAssay Description:All experiments were performed on a Biacore T100 at 25 deg C with a flow rate of 30 uL per minute. Double His-tagged HSP70 was immobilised on the sur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  71nMAssay Description:Binding affinity against HSPA1A (unknown origin) assessed as apparent dissociation constant incubated for 1 hr by colloidal coomassie staining based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM82124(adenosine-derived inhibitor (Grp78), 1)
Affinity DataKi:  110nM ΔG°:  -39.7kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32383(adenosine-derived inhibitor, 17)
Affinity DataKd:  120nMpH: 7.4 T: 2°CAssay Description:All experiments were performed on a Biacore T100 at 25 deg C with a flow rate of 30 uL per minute. Double His-tagged HSP70 was immobilised on the sur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32378(adenosine-derived inhibitor (Grp78), 13 | adenosin...)
Affinity DataKi:  120nM ΔG°:  -39.5kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 150nMAssay Description:Inhibition of HSPA1A (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32379(adenosine-derived inhibitor, 13)
Affinity DataKd:  200nMpH: 7.4 T: 2°CAssay Description:All experiments were performed on a Biacore T100 at 25 deg C with a flow rate of 30 uL per minute. Double His-tagged HSP70 was immobilised on the sur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32378(adenosine-derived inhibitor (Grp78), 13 | adenosin...)
Affinity DataKd:  300nMpH: 7.4 T: 2°CAssay Description:All experiments were performed on a Biacore T100 at 25 deg C with a flow rate of 30 uL per minute. Double His-tagged HSP70 was immobilised on the sur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32378(adenosine-derived inhibitor (Grp78), 13 | adenosin...)
Affinity DataKd:  300nMpH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32381(adenosine-derived inhibitor (Grp78), 14 | adenosin...)
Affinity DataKi:  310nM ΔG°:  -37.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM41998(cid_5351983 | (9Z)-9-[3,3-bis(oxidanyl)prop-2-enyl...)
Affinity DataIC50: 332nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32383(adenosine-derived inhibitor, 17)
Affinity DataIC50: 400nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM82127((2R,3R,4S,5R)-2-(6-Amino-8-methylaminopurin-9-yl)-...)
Affinity DataKi:  450nM ΔG°:  -36.2kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32378(adenosine-derived inhibitor (Grp78), 13 | adenosin...)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM82124(adenosine-derived inhibitor (Grp78), 1)
Affinity DataKd:  500nMpH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM2(CHEMBL14249 | ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-pu...)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM31995(ADP | CHEMBL14830 | Adenosine Diphosphate (ADP))
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM31995(ADP | CHEMBL14830 | Adenosine Diphosphate (ADP))
Affinity DataKd:  500nMpH: 7.4 T: 2°CAssay Description:All experiments were performed on a Biacore T100 at 25 deg C with a flow rate of 30 uL per minute. Double His-tagged HSP70 was immobilised on the sur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataIC50: 578nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32382(adenosine-derived inhibitor, 16)
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM42000(cid_274125 | 7-methyl-2-[3,4,5-tris(oxidanyl)-6-ox...)
Affinity DataIC50: 634nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataIC50: 760nMpH: 7.0 T: 2°CAssay Description:Burnham Center for Chemical Genomics (BCCG) Burnham Institute for Medical Research (San Diego, CA) NIH Molecular Libraries Screening Centers Network ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2009
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32381(adenosine-derived inhibitor (Grp78), 14 | adenosin...)
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32377(adenosine-derived inhibitor (Grp78), 12 | adenosin...)
Affinity DataKi:  1.05E+3nM ΔG°:  -34.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM82125((2R,3R,4S,5R)-2-(6-Amino-8-methylaminopurin-9-yl)-...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32375(adenosine-derived inhibitor (Grp78), 9 | adenosine...)
Affinity DataKi:  1.29E+3nM ΔG°:  -33.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32379(adenosine-derived inhibitor, 13)
Affinity DataIC50: 1.30E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32376(adenosine-derived inhibitor (Grp78), 11 | adenosin...)
Affinity DataKi:  1.44E+3nM ΔG°:  -33.3kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM50652104(CHEMBL5639838)
Affinity DataKd:  1.63E+3nMAssay Description:Binding affinity to HSPA1A (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32380(adenosine-derived inhibitor, 14)
Affinity DataIC50: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM82128(2-[(2R,3S,4R,5R)-5-(6-Amino-8-methylaminopurin-9-y...)
Affinity DataKi:  1.85E+3nM ΔG°:  -32.7kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM41993(cid_2868734 | MLS-0111570.0001 | 8-sulfamoyl-3a,4,...)
Affinity DataIC50: 1.97E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32377(adenosine-derived inhibitor (Grp78), 12 | adenosin...)
Affinity DataIC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31733(cid_4039540 | MLS-0092010.0001 | 3a,4,5,9b-tetrahy...)
Affinity DataIC50: 2.42E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32375(adenosine-derived inhibitor (Grp78), 9 | adenosine...)
Affinity DataIC50: 2.90E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM41996(cid_3439114 | MLS-0092009.0001 | 6-iodanyl-3a,4,5,...)
Affinity DataIC50: 3.13E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32376(adenosine-derived inhibitor (Grp78), 11 | adenosin...)
Affinity DataIC50: 3.20E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31729(cid_3136927 | CHEMBL201289 | MLS-0111575.0001 | 8-...)
Affinity DataIC50: 3.24E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50192459(adenosine 5'-triphosphate(4-) | cid_16654697 | ATP...)
Affinity DataIC50: 3.37E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM82126((2R,3R,4S,5R)-2-(6-Amino-8-methylaminopurin-9-yl)-...)
Affinity DataKi:  4.07E+3nM ΔG°:  -30.8kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32380(adenosine-derived inhibitor, 14)
Affinity DataKd:  4.20E+3nMpH: 7.4 T: 2°CAssay Description:All experiments were performed on a Biacore T100 at 25 deg C with a flow rate of 30 uL per minute. Double His-tagged HSP70 was immobilised on the sur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32373(adenosine-derived inhibitor (Grp78), 8 | adenosine...)
Affinity DataKi:  4.31E+3nM ΔG°:  -30.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM82129((2R,3R,4S,5R)-2-{6-Amino-8-[(quinolin-2-ylmethyl)a...)
Affinity DataKi:  4.32E+3nM ΔG°:  -30.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32370(adenosine-derived inhibitor (Grp78), 2 | adenosine...)
Affinity DataKi:  4.46E+3nM ΔG°:  -30.5kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(MLS-0067149.0001 | cid_646096 | 8-methyl-3a,4,5,9b...)
Affinity DataIC50: 4.77E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM32374(adenosine-derived inhibitor, 8)
Affinity DataIC50: 4.90E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31734(MLS-0025126.0001 | 8-ethoxycarbonyl-3a,4,5,9b-tetr...)
Affinity DataIC50: 5.56E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetHeat shock 70 kDa protein 1A(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31723(MLS-0111569.0001 | cid_3112185 | 8-nitro-3a,4,5,9b...)
Affinity DataIC50: 6.06E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
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