Compile Data Set for Download or QSAR
Report error Found 219 Enz. Inhib. hit(s) with Target = 'Malate dehydrogenase, mitochondrial'
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  20nMAssay Description:Binding affinity to human MDH2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  53nMAssay Description:Binding affinity to human MDH2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 23229BDBM23229([(4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)methyl]car...)
Affinity DataIC50: 390nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300050BDBM50300050(9-tert-Butyl-5-(3,4-dichlorobenzyl)-7,12-dihydroin...)
Affinity DataIC50: 770nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250242BDBM50250242(CHEMBL4068781 | US12630497, Compound 9-2)
Affinity DataKi:  950nMAssay Description:Competitive inhibition of human MDH2 using oxaloacetic acid as substrate in presence of NADH after 30 mins by double reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250242BDBM50250242(CHEMBL4068781 | US12630497, Compound 9-2)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300053BDBM50300053(9-Bromo-5-(3,4-dichlorobenzyl)-7,12-dihydroindolo[...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250244BDBM50250244(CHEMBL4091027 | US12630497, Compound 3-33)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250221BDBM50250221(CHEMBL4080721 | US12630497, Compound 3-34)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250243BDBM50250243(CHEMBL4074947 | US12630497, Compound 3-30)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250220BDBM50250220(CHEMBL4098767 | US12630497, Compound 3-29)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 50404710BDBM50404710(CHEMBL434275)
Affinity DataIC50: 1.48E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250227BDBM50250227(CHEMBL4073085 | US12630497, Compound 3-13)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 50404709BDBM50404709(CHEMBL156707)
Affinity DataIC50: 1.58E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300055BDBM50300055(9-Bromo-5-(4-methylbenzyl)-7,12-dihydroindolo[3,2-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300059BDBM50300059(5-Benzyl-9-tert-butyl-7,12-dihydroindolo[3,2-d][1]...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250230BDBM50250230(CHEMBL4087903 | US12630497, Compound 3-27)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300054BDBM50300054(9-Bromo-5-(4-methoxybenzyl)-7,12-dihydroindolo[3,2...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 50404705BDBM50404705(CHEMBL348630)
Affinity DataIC50: 1.82E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250235BDBM50250235(CHEMBL4065526 | US12630497, Compound 3-12)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400094BDBM50400094(CHEMBL427092 | US12630497, Compound 3-20)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of MDH2 (unknown origin) using varying NADH level by oxaloacetate-dependent NADH oxidation based Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 50404703BDBM50404703(CHEMBL155684)
Affinity DataIC50: 2.19E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7307BDBM7307(CHEMBL99779 | NSC 702377 | 8-benzyl-14-bromo-8,18-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 50404702BDBM50404702(CHEMBL160429)
Affinity DataIC50: 2.45E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 50404714BDBM50404714(CHEMBL160432)
Affinity DataIC50: 2.51E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300044BDBM50300044(Octyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]ben...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300060BDBM50300060(5-Benzyl-9-chloro-7,12-dihydroindolo[3,2-d][1]benz...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 23227BDBM23227([(4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)methyl]car...)
Affinity DataIC50: 2.72E+3nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 23223BDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataIC50: 2.80E+3nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250226BDBM50250226(CHEMBL4099949 | US12630497, Compound 3-14)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400092BDBM50400092(CHEMBL2178409 | US12630497, Compound 6-2)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400095BDBM50400095(CHEMBL2178407 | US12630497, Compound 6-1)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250226BDBM50250226(CHEMBL4099949 | US12630497, Compound 3-14)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250243BDBM50250243(CHEMBL4074947 | US12630497, Compound 3-30)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250242BDBM50250242(CHEMBL4068781 | US12630497, Compound 9-2)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250227BDBM50250227(CHEMBL4073085 | US12630497, Compound 3-13)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250220BDBM50250220(CHEMBL4098767 | US12630497, Compound 3-29)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250235BDBM50250235(CHEMBL4065526 | US12630497, Compound 3-12)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808071BDBM808071(Methyl 4-(4-methoxybenzyloxy)-3-(2-(4-(2,4,4-trime...)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808087BDBM808087((E)-methyl 4-hydroxy-3-(3-(4-(2,4,4-trimethylpenta...)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250230BDBM50250230(CHEMBL4087903 | US12630497, Compound 3-27)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250221BDBM50250221(CHEMBL4080721 | US12630497, Compound 3-34)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250244BDBM50250244(CHEMBL4091027 | US12630497, Compound 3-33)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400096BDBM50400096(CHEMBL2178406 | US12630497, Compound 3-32)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250218BDBM50250218(CHEMBL4074694 | US12630497, Compound 9-3)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 50404726BDBM50404726(CHEMBL160455)
Affinity DataIC50: 4.07E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300058BDBM50300058(5-Benzyl-9-trifluoromethyl-7,12-dihydroindolo[3,2-...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031520BDBM50031520(CHEMBL3359147)
Affinity DataKi:  4.30E+3nMAssay Description:Competitive inhibition of MDH2 (unknown origin) using varying NADH level by oxaloacetate-dependent NADH oxidation based Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300045BDBM50300045(Hexyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]ben...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300046BDBM50300046(Pentyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]be...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
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