Compile Data Set for Download or QSAR
Report error Found 21305 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor'
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50430798(CHEMBL2335120)
Affinity DataEC50:  0.0000420nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells after 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50430801(CHEMBL2334776)
Affinity DataEC50:  0.0000910nMAssay Description:Agonist activity at FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50430803(CHEMBL2334774)
Affinity DataEC50:  0.000107nMAssay Description:Agonist activity at FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50430802(CHEMBL2334775)
Affinity DataEC50:  0.000109nMAssay Description:Agonist activity at FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50430799(CHEMBL2334772)
Affinity DataEC50:  0.000130nMAssay Description:Agonist activity at FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50594825(CHEMBL5198856)
Affinity DataEC50:  0.000515nMAssay Description:Agonist activity at MOP (unknown origin) stably expressed in HEK293 cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50430800(CHEMBL2334773)
Affinity DataEC50:  0.000516nMAssay Description:Agonist activity at FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111903((S)-1-[(S)-2-{2-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  0.000540nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50133817(BCTC | CHEMBL441472 | N-(4-tert-butylphenyl)-4-(3-...)
Affinity DataKi:  0.000950nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  0.00100nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50292912(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy...)
Affinity DataKi:  0.00130nMAssay Description:Displacement of [3H]-DAMGO from human HA-tagged mu-opioid receptor expressed in HEK293 cells after 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50402775(CHEMBL2208351)
Affinity DataKi:  0.00160nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50393257(CHEMBL2151735)
Affinity DataEC50:  0.00174nMAssay Description:Agonist activity at human MOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50528967(CHEMBL4439415)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50528966(CHEMBL4521879)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50528960(CHEMBL4450250)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50528965(CHEMBL4550234)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50594821(CHEMBL5175179)
Affinity DataEC50:  0.00180nMAssay Description:Agonist activity at MOP (unknown origin) stably expressed in HEK293 cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50648331(CHEMBL5613639)
Affinity DataKi:  0.00200nMAssay Description:Binding affinity to human mu-opioid receptor extracted from CHO cell membrane assessed as inhibition constant incubated for 60 mins in presence of [3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50594822(CHEMBL5182849)
Affinity DataEC50:  0.00201nMAssay Description:Agonist activity at MOP (unknown origin) stably expressed in HEK293 cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125999((R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataKi:  0.00205nMAssay Description:Ability to displace [3H]DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190307(Ac-RYYRIK-GGG-K-(NH2)-YAFGYPS-GG | CHEMBL414736)
Affinity DataIC50: 0.00236nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  0.00240nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50529413(CHEMBL4563672)
Affinity DataEC50:  0.00240nMAssay Description:Agonist activity at human MOR expressed in CHO-K1 cells assessed as cAMP accumulation incubated for 30 mins and measured after 1 hr by Eu-cAMP tracer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50408679(CHEMBL5287792)
Affinity DataKi:  0.00260nMAssay Description:Displacement of [3H] DAMGO from mouse MOR expressed in CHO cell membrane incubated for 90 mins by scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50274679(CHEMBL4128530)
Affinity DataEC50:  0.00300nMAssay Description:Agonist activity at rat mu-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50366764(MCL-117 | CHEMBL1790045)
Affinity DataKi:  0.00300nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50366764(MCL-117 | CHEMBL1790045)
Affinity DataKi:  0.00320nMAssay Description:Binding affinity towards Opioid receptor mu 1 in guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50408509(CHEMBL5277326)
Affinity DataKi:  0.00340nMAssay Description:Displacement of [3H] DAMGO from mouse MOR expressed in CHO cell membrane incubated for 90 mins by scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50430798(CHEMBL2335120)
Affinity DataKi:  0.00372nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells after 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50594820(CHEMBL5176887)
Affinity DataEC50:  0.00400nMAssay Description:Agonist activity at MOP (unknown origin) stably expressed in HEK293 cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50451302(CHEMBL2115245)
Affinity DataKi:  0.00480nMAssay Description:Binding affinity towards Opioid receptor mu 1 in guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataEC50:  0.00490nMAssay Description:Agonist activity at human MOR expressed in CHO-K1 cells assessed as cAMP accumulation incubated for 30 mins and measured after 1 hr by Eu-cAMP tracer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50402777(CHEMBL2208347)
Affinity DataKi:  0.00490nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50033531(N-[1-(2-Hydroxy-2-phenyl-ethyl)-3-methyl-piperidin...)
Affinity DataKi:  0.00500nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50229232(CHEMBL610527)
Affinity DataKi:  0.00500nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50033532(N-[(3S,4R)-1-((R)-2-Hydroxy-2-phenyl-ethyl)-3-meth...)
Affinity DataKi:  0.00500nMAssay Description:Binding affinity towards Opioid receptor mu 1 using [3H]DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50529410(CHEMBL4463749)
Affinity DataEC50:  0.00510nMAssay Description:Agonist activity at human MOR expressed in CHO-K1 cells assessed as cAMP accumulation incubated for 30 mins and measured after 1 hr by Eu-cAMP tracer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50033536(CHEMBL121494 | N-[(3R,4R)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi:  0.00550nMAssay Description:Binding affinity towards Opioid receptor mu 1 using [3H]DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50402777(CHEMBL2208347)
Affinity DataKi:  0.00560nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50402776(CHEMBL2208349)
Affinity DataKi:  0.00560nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50274694(CHEMBL4129901)
Affinity DataEC50:  0.00600nMAssay Description:Agonist activity at rat mu-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50551316(CHEMBL4776706)
Affinity DataKi:  0.00630nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096716(Enkephalin derivative | CHEMBL100480)
Affinity DataKi:  0.00680nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50010532(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50: 0.00700nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50402772(CHEMBL2208350)
Affinity DataKi:  0.00710nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50274686(CHEMBL4129679)
Affinity DataEC50:  0.00800nMAssay Description:Agonist activity at rat mu-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50430806(CHEMBL2334771)
Affinity DataEC50:  0.00853nMAssay Description:Agonist activity at FLAG-tagged mu-type opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50008834(CHEMBL3236671)
Affinity DataKi:  0.00935nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  0.00950nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
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