Compile Data Set for Download or QSAR
Report error Found 648 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacylase sirtuin-5, mitochondrial'
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255700(CHEMBL4091790)
Affinity DataKd:  0.0100nMAssay Description:Binding affinity to human N-terminal biotinylated SIRT5 by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255714(CHEMBL4064460)
Affinity DataKd:  0.120nMAssay Description:Binding affinity to human N-terminal biotinylated SIRT5 by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598638(CHEMBL5199270)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255730(CHEMBL4065067)
Affinity DataKi:  3.5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255692(CHEMBL4100475)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255690(CHEMBL4068735)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255693(CHEMBL4073655)
Affinity DataKi:  3.5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255691(CHEMBL4092751)
Affinity DataKi:  3.5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataKi:  6nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255710(CHEMBL4091258)
Affinity DataKi:  7nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598639(CHEMBL5209031)
Affinity DataKi:  7nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255714(CHEMBL4064460)
Affinity DataKi:  14nMAssay Description:Competitive inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255710(CHEMBL4091258)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255714(CHEMBL4064460)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598635(CHEMBL5172115)
Affinity DataKi:  22nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255740(CHEMBL4100351)
Affinity DataKi:  23nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255700(CHEMBL4091790)
Affinity DataIC50: 30nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255700(CHEMBL4091790)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598634(CHEMBL5188575)
Affinity DataKi:  37nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255635(CHEMBL4065953)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255740(CHEMBL4100351)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255711(CHEMBL4083471)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255726(CHEMBL4085990)
Affinity DataKi:  83nMAssay Description:Competitive inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255743(CHEMBL4084850)
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255774(CHEMBL4101463)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255726(CHEMBL4085990)
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255701(CHEMBL4079616)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50041802(CHEMBL46469 | 1,8-dihydroxyanthrone | 1,8-dihydrox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50041802(CHEMBL46469 | 1,8-dihydroxyanthrone | 1,8-dihydrox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SIRT5 (unknown origin) using GGQSLK[succ]FGKG as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255741(CHEMBL4078223)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataIC50: 110nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595086(CHEMBL5177283)
Affinity DataIC50: 110nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataIC50: 110nMAssay Description:Inhibition of human SIRT5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataIC50: 110nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255639(CHEMBL4097208)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255644(CHEMBL4079212)
Affinity DataKi:  135nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255659(CHEMBL4092610)
Affinity DataIC50: 177nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255703(CHEMBL4063400)
Affinity DataIC50: 207nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 in presence of 200 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 in presence of 10 uM Ac-K(Suc)-AMC by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595086(CHEMBL5177283)
Affinity DataIC50: 230nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 240nMAssay Description:Inhibition of human SIRT5 in presence of 400 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 250nMAssay Description:Inhibition of human SIRT5 in presence of 800 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595085(CHEMBL5197912)
Affinity DataIC50: 260nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SIRT5 in presence of 100 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SIRT5 in presence of 50 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255725(CHEMBL4068365)
Affinity DataKi:  263nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255644(CHEMBL4079212)
Affinity DataIC50: 274nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598637(CHEMBL5185695)
Affinity DataIC50: 290nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
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