Compile Data Set for Download or QSAR
Report error Found 325 Enz. Inhib. hit(s) with Target = 'Neuropeptide FF receptor 2'
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565178(CHEMBL4460742)
Affinity DataKi:  0.0270nMAssay Description:Displacement of [125I]EYF from human NPFFR2 expressed in CHO cells by gamma-counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565182(CHEMBL4797394)
Affinity DataKi:  0.0770nMAssay Description:Displacement of [125I]-1-DMe-NPFF from human NPFF2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037567(2-[(Pyrrolidine-2-carbonyl)-amino]-pentanedioic ac...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037568(2-{[1-(2-{2-[2-(2-Amino-3-(p-hydroxyphenyl)-propio...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037559((S)-2-[((S)-1-{(S)-2-[(S)-2-((S)-2-Amino-4-methyl-...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037575(2-Amino-pentanedioic acid 5-amide 1-{[1-(1-carbamo...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to human NPFFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  0.210nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037572(2-{[1-(2-{2-[2-(2-Amino-3-(p-hydroxyphenyl)-propio...)
Affinity DataKi:  0.220nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to human NPFFR2 expressed in green monkey COS-7 cell membranes by [125I]-1DMeNPFF radioligand based saturation binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037565((S)-2-({(S)-1-[(S)-2-((S)-2-Amino-3-phenyl-propion...)
Affinity DataKi:  0.430nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50029138(CHEMBL3360830)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]EYF from human NPFF2 receptor expressed in CHO cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037563(2-{[1-(2-{2-[2-(2-Amino-3-(p-hydroxyphenyl)-propio...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50159227(CHEMBL3786309)
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]EYE from human NPFF2 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation spectrophotometric countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50159227(CHEMBL3786309)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to human NPFF2 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation spectrophotometric countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037576(1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4-met...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50336911((S)-2-((S)-2-((S)-5-amino-2-((S)-1-((S)-2-((S)-2-(...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of (D-[125I]Tyr1, MePhe3)-NPFF from NPFFR2 after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50029138(CHEMBL3360830)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]EYF from human NPFF2 receptor expressed in CHO cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50029188(CHEMBL2165920)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037564(2-{[1-(2-{2-[2-(2-Amino-3-(p-hydroxyphenyl)-propio...)
Affinity DataKi:  1nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Mouse)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-1DMeNPFF from mouse NPFF2R receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]EYE from human NPFF2 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation spectrophotometric countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037569(2-(2-Amino-3-phenyl-propionylamino)-4-methyl-penta...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565189(CHEMBL4779743)
Affinity DataKi:  1.40nMAssay Description:Displacement of TAMRA-NPFF from human NPFFR2 expressed in CHO-K1 cells preincubated for 15 mins followed by GTPgammaS addition and measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM86143(RFamide-related peptide 3 | L-Val-L-Pro-L-Asn-L-Le...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037567(2-[(Pyrrolidine-2-carbonyl)-amino]-pentanedioic ac...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]-1DMeNPFF from rat NPFFR2 expressed in HEK293 cells incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565190(CHEMBL4800299)
Affinity DataKi:  2.20nMAssay Description:Displacement of TAMRA-NPFF from human NPFFR2 expressed in CHO-K1 cells preincubated for 15 mins followed by GTPgammaS addition and measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50029138(CHEMBL3360830)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human NPFF2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037567(2-[(Pyrrolidine-2-carbonyl)-amino]-pentanedioic ac...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]-1DMeNPFF from human NPFFR2 expressed in HEK293 cells incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565183(CHEMBL4790994)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]-1-DMe-NPFF from human NPFF2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583768(CHEMBL5093771)
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50637851(CHEMBL5567081)
Affinity DataKi:  3.90nMAssay Description:Displacement of [125I]-1-DMe-NPFF from human NPFF2 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50402444(CHEMBL2208319)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]FFRF-NH2 from human flag-tagged NPFF2 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50402453(CHEMBL2208338)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]FFRF-NH2 from human flag-tagged NPFF2 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50636418(CHEMBL5568142)
Affinity DataKi:  4.70nMAssay Description:Displacement of [125I]-1DMeNPFF from human NPFFR2 expressed in CHO cell membrane incubated for 1 hr by Topcount counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM86140(NSC_123797 | CAS_123797 | NPFF)
Affinity DataKi:  5.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2012
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM86142(CAS_132709 | NSC_132709 | 1DMe-Y8Fa)
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2012
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50034115(1N-[1-carbamoyl-2-phenyl-(1S)-ethyl]-5-amino(imino...)
Affinity DataKi:  6.60nMAssay Description:Displacement of [125I]EYF from human NPFFR2 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565183(CHEMBL4790994)
Affinity DataKi:  8.40nMAssay Description:Displacement of [125I]-1DMeNPFF from human NPFFR2 expressed in CHO cell membrane incubated for 1 hr by Topcount counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50402451(CHEMBL2208322)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]FFRF-NH2 from human flag-tagged NPFF2 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037558(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  10nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565182(CHEMBL4797394)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells by [35S]-GTP S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM86147(CAS_68615 | NSC_68615 | FMRFamide)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2012
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM86145(RFamide-related peptide 1 | L-Met-L-Pro-L-His-L-Se...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2012
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Rat)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037573((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...)
Affinity DataKi:  15.5nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50555154(CHEMBL4800237)
Affinity DataEC50:  19nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in HEK293-A cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM86139(CAS_235433-36-0 | PrRP31 | CAS_99566-27-5 | NSC_0 ...)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 325 total ) | Next | Last >>
Jump to: