Compile Data Set for Download or QSAR
Report error Found 1144 Enz. Inhib. hit(s) with Target = 'Prostaglandin F2-alpha receptor'
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520924(US11149018, Example 205)
Affinity DataIC50: 0.410nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM50085910(CLOPROSTENOL | CHEMBL37853 | (Z)-7-{(1R,2R,3R,5S)-...)
Affinity DataKi:  0.470nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520771(US11149018, Example 58)
Affinity DataIC50: 0.520nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520770(US11149018, Example 57 | (+/−)-5-[({6-Bromo-...)
Affinity DataIC50: 0.530nMAssay Description:Antagonist activity at human FPR expressed in human Chem-1 cells assessed as inhibition of PGF2alpha-induced calcium flux preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520770(US11149018, Example 57 | (+/−)-5-[({6-Bromo-...)
Affinity DataIC50: 0.530nMAssay Description:Antagonist activity at human FPR expressed in human Chem-1 cells assessed as inhibition of PGF2alpha-induced calcium flux preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520911(US11149018, Example 193)
Affinity DataIC50: 0.620nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520868(US11149018, Example 152)
Affinity DataIC50: 0.630nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520929(US11149018, Example 210)
Affinity DataIC50: 0.680nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520869(US11149018, Example 274 | US11149018, Example 153)
Affinity DataIC50: 0.730nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520939(US11149018, Example 220)
Affinity DataIC50: 0.760nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520843(US11149018, Example 127)
Affinity DataIC50: 0.790nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520770(US11149018, Example 57 | (+/−)-5-[({6-Bromo-...)
Affinity DataIC50: 0.830nMAssay Description:Antagonist activity at human FPR expressed in human Chem-1 cells assessed as inhibition of PGF2alpha-induced calcium flux preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520774(US11149018, Example 61)
Affinity DataIC50: 0.830nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520770(US11149018, Example 57 | (+/−)-5-[({6-Bromo-...)
Affinity DataIC50: 0.840nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520844(US11149018, Example 272 | US11149018, Example 128)
Affinity DataIC50: 0.850nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523442(US11136296, Example 173 | US11136296, Example 250 ...)
Affinity DataIC50: 0.960nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGF2-alpha from human FP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM50085910(CLOPROSTENOL | CHEMBL37853 | (Z)-7-{(1R,2R,3R,5S)-...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGF2-alpha from human FP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM50547366(CHEMBL4761725)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGF2alpha from full-length recombinant human FP receptor expressed in HEK293 cell membranes measured after 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM244799(US9447055, I)
Affinity DataKi:  1nMAssay Description:The potency of inhibition of compound I and compound II on prostaglandin F2α receptor was assessed by analyzing the affinity of these compounds...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520944(US11149018, Example 228 | 5-[({6-Bromo-2-[3-ethylp...)
Affinity DataIC50: 1.10nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523442(US11136296, Example 173 | US11136296, Example 250 ...)
Affinity DataIC50: 1.10nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520852(US11149018, Example 136)
Affinity DataIC50: 1.10nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520761(US11149018, Example 48)
Affinity DataIC50: 1.20nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523470(US11136296, Example 201)
Affinity DataIC50: 1.20nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520937(US11149018, Example 218)
Affinity DataIC50: 1.20nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520867(US11149018, Example 151 | (+/−)-5-({[6-Bromo...)
Affinity DataIC50: 1.30nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520759(US11149018, Example 46)
Affinity DataIC50: 1.30nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520927(US11149018, Example 208)
Affinity DataIC50: 1.40nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520877(US11149018, Example 161)
Affinity DataIC50: 1.40nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520954(US11149018, Example 235 | (+)-5-({[6-Bromo-3-methy...)
Affinity DataIC50: 1.40nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520958(US11149018, Example 239 | (+)-5-({[2-(Azepan-1-yl)...)
Affinity DataIC50: 1.40nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520861(US11149018, Example 145)
Affinity DataIC50: 1.5nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520855(US11149018, Example 139 | 5-[({6-Bromo-2-[3-ethylp...)
Affinity DataIC50: 1.5nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520918(US11149018, Example 199)
Affinity DataIC50: 1.60nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520901(US11149018, Example 183)
Affinity DataIC50: 1.60nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523496(US11136296, Example 227)
Affinity DataIC50: 1.60nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520874(US11149018, Example 158 | 5-[({6-Bromo-2-[3-ethylp...)
Affinity DataIC50: 1.60nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520921(US11149018, Example 202)
Affinity DataIC50: 1.70nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520873(US11149018, Example 157 | 5-[({6-Bromo-3-methyl-2-...)
Affinity DataIC50: 1.70nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523480(US11136296, Example 211)
Affinity DataIC50: 1.70nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520842(US11149018, Example 126 | (+/−)-5-({[6-Bromo...)
Affinity DataIC50: 1.70nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520945(US11149018, Example 226)
Affinity DataIC50: 1.80nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523478(US11136296, Example 209 | (+/-)-5-{[(6-Bromo-3-met...)
Affinity DataIC50: 1.80nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520931(US11149018, Example 212)
Affinity DataIC50: 1.90nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Mouse)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50247862(5Z-(9S,11R,15S)-13-Oxa-17-(3-trifluoromethyl)pheny...)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at FP receptor in Swiss mouse 3T3 cells assessed as [3H]-IP accumulation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520935(US11149018, Example 282 | US11149018, Example 216)
Affinity DataIC50: 1.90nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520849(US11149018, Example 133)
Affinity DataIC50: 2nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523505(US11136296, Example 236)
Affinity DataIC50: 2nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM50085910(CLOPROSTENOL | CHEMBL37853 | (Z)-7-{(1R,2R,3R,5S)-...)
Affinity DataIC50: 2nMAssay Description:Affinity for human Prostanoid FP receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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