Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with Target = 'Zinc finger protein Helios'
TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526274(2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...)
Affinity DataEC50:  230nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM525983(3-(5-(methyl((1R,2R)-2- (methylamino)cyclohexyl)am...)
Affinity DataEC50: >3.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526283(US11185537, Compound 1-148)
Affinity DataEC50:  1.13E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526282(5-(((1S,2S)-2- (dimethylamino)cyclohexyl)amino)-2-...)
Affinity DataEC50:  410nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526281(5-(((1S,2S)-2- (dimethylamino)cyclohexyl) (methyl)...)
Affinity DataEC50:  1.57E+3nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526280(3-(5-(((1S,2S)-2- (methylamino)cyclohexyl)amino)-1...)
Affinity DataEC50:  990nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526279(2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...)
Affinity DataEC50: >3.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526278(3-(4-fluoro-5-(methyl((1S,2S)-2- (methylamino)cycl...)
Affinity DataEC50:  66nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526276(2-(2,6-dioxopiperidin-3-yl)-5- (methyl((1S,2S)-2- ...)
Affinity DataEC50:  2.31E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526275(5-(((1S,2S)-2- (benzylamino)cyclohexyl) (methyl)am...)
Affinity DataEC50:  450nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526270(US11185537, Compound Mix)
Affinity DataEC50:  670nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526273(2-(2,6-dioxopiperidin-3-yl)-5-(((1S,2S)-2- (ethyla...)
Affinity DataEC50:  49nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526272(5-(((1S,2S)-2-aminocyclohexyl) (methyl)amino)- 2-(...)
Affinity DataEC50:  150nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526131(3-(5-(((1S,2S)-2- aminocyclohexyl)amino)-1- oxoiso...)
Affinity DataEC50:  183nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526006(3-(5-(((1S,2S)-2- (benzylamino)cyclohexyl)amino)-1...)
Affinity DataEC50:  29nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50:  113nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526123(3-(5-(((1S,2S)-2- (benzyl(methyl)amino)cyclohexyl)...)
Affinity DataEC50:  43nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526271(2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...)
Affinity DataEC50:  24nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50:  103nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526253(3-(5-(((1S,2S)-2-(ethylamino) cyclohexyl)amino)- 1...)
Affinity DataEC50:  1.67E+3nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526265(3-(5-(((1S,2S)-2- (isopropylamino)cyclohexyl)amino...)
Affinity DataEC50:  100nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526267(3-(5-(((1S,2S)-2- ((cyclohexylmethyl)amino) cycloh...)
Affinity DataEC50:  36nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526268(3-(1-oxo-5-(((1S,2S)-2-(piperidin-1- yl)cyclopenty...)
Affinity DataEC50:  730nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526269(3-(5-(((1S,2S)-2- (isobutylamino)cyclohexyl)amino)...)
Affinity DataEC50:  940nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526270(US11185537, Compound Mix)
Affinity DataEC50:  230nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756484(3-(1-(4-methylbenzyl)-7'-oxo- 2',3',7',9'-tetrahyd...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756511(3-(1'-(3-(1-(oxetan-3-yl)-1H-pyrazol- 4-yl)benzyl)...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756510(3-(1'-(3-(1H-pyrazol-3-yl)benzyl)-6- oxo-6,8-dihyd...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756509(3-(1'-(3-(1-ethyl-1H-pyrazol-4- yl)benzyl)-6-oxo-6...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756503(3-(1'-((1H-indol-6-yl)methyl)-6-oxo- 6,8-dihydro-2...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756490(3-(1'-((1H-indazol-7-yl)methyl)-6- oxo-6,8-dihydro...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756483(3-(1-(4-ethylbenzyl)-7'-oxo-2',3',7',9'- tetrahydr...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756480(3-(1'-(4-(difluoromethyl)benzyl)-6- oxo-6,8-dihydr...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756482(3-(1'-benzyl-6-oxo-6,8-dihydro- 2H,7H-spiro[furo[2...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756512((S)-3-(1'-(3-(1-methyl-1H-pyrazol-4- yl)benzyl)-6-...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756479(3-(7'-oxo-2',3',7',9'-tetrahydro-8'H- spiro[piperi...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756508(3-(1'-(3-(1-methyl-1H-pyrazol-3- yl)benzyl)-6-oxo-...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756507(3-(6-oxo-1'-(3-(pyridin-4-yl)benzyl)- 6,8-dihydro-...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756506(3-(6-oxo-1'-(3-(pyridin-3-yl)benzyl)- 6,8-dihydro-...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756505(3-(6-oxo-1'-((2-oxoindolin-6- yl)methyl)-6,8-dihyd...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756504(3-(1'-((1-methyl-1H-indol-6- yl)methyl)-6-oxo-6,8-...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756502(3-(1'-((6-chloro-1H-indazol-4- yl)methyl)-6-oxo-6,...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756501(3-(1'-((6-bromo-1H-indazol-4- yl)methyl)-6-oxo-6,8...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756500(3-(1'-(3-((1H-pyrazol-1- yl)methyl)benzyl)-6-oxo-6...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756499(3-(1'-(3-(oxazol-5-yl)benzyl)-6-oxo- 6,8-dihydro-2...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756497(3-(6-oxo-1'-((3-oxoisoindolin-5- yl)methyl)-6,8-di...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756485(3-(1'-(4-methylbenzyl)-6-oxo-6,8- dihydro-2H,7H-sp...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756486(3-(1'-(naphthalen-1-ylmethyl)-6-oxo- 6,8-dihydro-2...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM756488(3-(1'-(3,5-dimethylbenzyl)-6-oxo-6,8- dihydro-2H,7...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent

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