Report error Found 440 with Last Name = 'staels' and Initial = 'b'
Affinity DataKi: 8nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: 18.4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54.2nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: 254nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 618nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human NEP-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human ACE-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (1 to 40) hydrolysis preincubated for 10 mins measured after 30 mins by spectrophotometer a...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NEP-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant ECE1-mediated amyloid beta hydrolysis after 45 mins by fluorimetry assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ACE-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant ACE2-mediated amyloid beta hydrolysis using Mca-Tyr-Val-Ala-Asp-Pro-Ala-Lys-(DNP)-OH as substrate after 20 mins by fl...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP13-mediated amyloid beta hydrolysis after 10 mins by fluorimetry assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP1-mediated amyloid beta hydrolysis using DNP-Pro-Cha-Gly- Cys(Me)-His-Ala- Lys(n-Me-Abz)-NH2 as substrate after 40...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
University of Lille
Curated by ChEMBL
University of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant TACE-mediated amyloid beta hydrolysis after 5 mins by fluorimetry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 530nMAssay Description:Induction of human recombinant IDE-mediated insulin hydrolysis preincubated for 10 mins measured after 30 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 700nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.57E+4nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.09E+5nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.25E+4nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.20E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.96E+4nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair